解剖学和形态学
麻醉学
听力与言语-语言病理学
行为科学
心脏和心血管系统
细胞和组织工程学
临床神经病学
危重症监护医学
牙科,口腔外科和医学
皮肤病学
急诊医学
内分泌学和新陈代谢
肠胃学和肝脏学
老人病学和老年医学
卫生保健科学和服务
血液学
免疫学
传染病
综合和补充性医学
医学伦理学
医学信息学
医学实验室技术
医学,全科和内科
医学,法律
医学,研究和试验
神经系统科学
护理
营养学和饮食学
产科医学和妇科医学
肿瘤学
眼科学
整形外科学
耳鼻喉科学
病理学
儿科学
周围血管疾病
药理学和药剂学
生理学
基本医疗保健
精神病学
公共、环境和职业卫生
放射学,核医学和医学成像
康复学
生殖生物学
呼吸系统
风湿病学
运动科学
外科学
毒理学
热带医学
泌尿学和肾脏学
病毒学
老年医学
健康政策和服务
心理学,临床
abstract:OBJECTIVE:The aim of this in vitro study was to compare fluorescence-aided caries excavation with conventional excavation based on the Martens and Vickers hardness of dentin at the cavity floor after caries removal. MATERIALS AND METHODS:In total, 20 extracted human teeth with dentin caries were bisected through the l...
journal_title:Clinical oral investigations
pub_type: 杂志文章
doi:10.1007/s00784-013-0999-y
更新日期:2014-01-01 00:00:00
abstract:OBJECTIVES:The main purpose of this prospective, double-blind, randomized study was to evaluate anaesthetic parameters, postoperative analgesia and vasoactive properties of levobupivacaine and bupivacaine for lower third molar surgery. MATERIAL AND METHODS:Sixty patients (ASA I) were scheduled for lower third molar su...
journal_title:Clinical oral investigations
pub_type: 杂志文章
doi:10.1007/s00784-013-1114-0
更新日期:2014-01-01 00:00:00
abstract:OBJECTIVES:The purpose of this study was to evaluate the effect of early functional loading to plateaued implants on bone formation and implant stability in a dog model. MATERIALS AND METHODS:Early loading (EL), nonloading control, and delayed loading (DL) groups were compared using six beagle dogs under functional lo...
journal_title:Clinical oral investigations
pub_type: 杂志文章
doi:10.1007/s00784-013-0929-z
更新日期:2014-01-01 00:00:00
abstract:OBJECTIVES:Intermittent parathyroid hormone (PTH) exerts anabolic effects on bone and has been approved for osteoporosis therapy. The dual actions of PTH are mediated primarily through the parathyroid hormone 1 receptor (PTH1R). Upon ligand binding, PTH1R activates diverse signaling pathways, including cAMP/protein kin...
journal_title:Clinical oral investigations
pub_type: 杂志文章
doi:10.1007/s00784-013-0985-4
更新日期:2014-01-01 00:00:00
abstract:OBJECTIVES:To evaluate the prevalence, clinical features, and risk factors of dentin hypersensitivity (DH) in a Brazilian population. MATERIALS AND METHODS:300 patients at the Dentistry Clinic of the University of São Paulo participated in this study. The subjects completed a questionnaire regarding their personal inf...
journal_title:Clinical oral investigations
pub_type: 杂志文章
doi:10.1007/s00784-013-1008-1
更新日期:2014-01-01 00:00:00
abstract:INTRODUCTION:Decay of teeth, erosion and disintegration of hard dental tissue are a clinically often seen side effect after radiotherapy for tumours in the head and neck region. To investigate if these side effects are due to structural changes in dental hard tissues, the current literature was searched. It can influen...
journal_title:Clinical oral investigations
pub_type: 杂志文章,评审
doi:10.1007/s00784-013-1034-z
更新日期:2014-01-01 00:00:00
abstract:OBJECTIVES:The aim of the study was to measure the percentage of volume of voids and gaps in the apical third of root canals obturated with two techniques using micro-computed tomography. MATERIALS AND METHODS:Fifty-four single-rooted teeth were collected and root canal-prepared. The roots were randomly allocated into...
journal_title:Clinical oral investigations
pub_type: 杂志文章
doi:10.1007/s00784-012-0875-1
更新日期:2013-11-01 00:00:00
abstract:OBJECTIVES:This study aimed to evaluate and correlate the efficacy and cytotoxicity of a 35 % hydrogen peroxide (HP) bleaching gel after different application times on dental enamel. MATERIALS AND METHODS:Enamel/dentin disks in artificial pulp chambers were placed in wells containing culture medium. The following grou...
journal_title:Clinical oral investigations
pub_type: 杂志文章
doi:10.1007/s00784-012-0883-1
更新日期:2013-11-01 00:00:00
abstract:OBJECTIVES:Several theories have been proposed regarding the genesis of sialoliths, including the organic core theory, which suggests epithelial or bacterial etiology originating in the central core. Our aim was to use novel methodologies to analyze central areas (the core) of calculi from sialolithiasis patients. MAT...
journal_title:Clinical oral investigations
pub_type: 杂志文章
doi:10.1007/s00784-012-0870-6
更新日期:2013-09-01 00:00:00
abstract:OBJECTIVES:The aims of this study are to evaluate the dentofacial morphology of patients with rheumatoid arthritis (RA) and to compare the morphological data with those of healthy age- and sex-matched control subjects. METHODS:Twenty-seven RA patients (mean age, 45.77 ± 8.64 years) and 25 healthy subjects (mean age, 4...
journal_title:Clinical oral investigations
pub_type: 杂志文章
doi:10.1007/s00784-012-0861-7
更新日期:2013-09-01 00:00:00
abstract:OBJECTIVE:The purpose of this study was to investigate the periodontal healing pattern of dehiscence-type defects following different chemical root conditioning modalities. MATERIALS AND METHODS:Buccal osseous dehiscence defects were created on six teeth of seven dogs. After dental plaque accumulation, defects were tr...
journal_title:Clinical oral investigations
pub_type: 杂志文章
doi:10.1007/s00784-012-0848-4
更新日期:2013-07-01 00:00:00
abstract:OBJECTIVES:The purpose of this study was to evaluate whether the current guidelines of the International Association of Dental Traumatology (IADT) for emergency care of traumatised teeth result in lower complication rates. MATERIALS AND METHODS:Therapeutic strategies of 361 dental injuries in 291 patients treated at a...
journal_title:Clinical oral investigations
pub_type: 杂志文章
doi:10.1007/s00784-012-0817-y
更新日期:2013-06-01 00:00:00
abstract:OBJECTIVE:This study aimed to measure modifications of mastication after immediate loading full-arch prosthesis (ILFAP) rehabilitation. MATERIALS AND METHOD:Fourteen patients were observed before and 6 months after ILFAP rehabilitation when masticating two natural, standardized foods (peanut and carrot) and three mode...
journal_title:Clinical oral investigations
pub_type: 杂志文章
doi:10.1007/s00784-012-0787-0
更新日期:2013-05-01 00:00:00
abstract:OBJECTIVE:Information about the spectrum of microorganisms in the intraimplant cavities of two-piece dental implants is scarce. The purpose of this study was to assess the intraimplant microflora of two-piece dental implants by conventional biochemical testing, matrix-assisted laser desorption/ionization time-of-flight...
journal_title:Clinical oral investigations
pub_type: 杂志文章
doi:10.1007/s00784-012-0805-2
更新日期:2013-05-01 00:00:00
abstract:OBJECTIVE:The purpose of this double-blind, randomised trial was to compare the clinical performance of a hybrid composite (Clearfil AP-X, Kuraray, Tokyo) and a nanocomposite (Filtek Z350, 3M ESPE, St. Paul, MN) over a period of 2 years in non-carious class V lesions using a modified US Public Health Service (USPHS) sy...
journal_title:Clinical oral investigations
pub_type: 杂志文章,随机对照试验
doi:10.1007/s00784-012-0780-7
更新日期:2013-04-01 00:00:00
abstract:OBJECTIVES:This study aimed to investigate the root canal morphology of mandibular first premolar teeth in a population from southwestern China by micro-computed tomography (micro-CT). MATERIALS AND METHODS:Human mandibular first premolars (115) were selected and prepared for micro-CT analysis with a slice thickness o...
journal_title:Clinical oral investigations
pub_type: 杂志文章
doi:10.1007/s00784-012-0778-1
更新日期:2013-04-01 00:00:00
abstract:OBJECTIVES:Candida albicans is the most common fungal pathogen in humans, but other Candida species cause candidosis. Candida species display significant differences in their susceptibility to antimycotic drugs. Patients with symptomatic or erythematous oral lichen planus (OLP) commonly have Candida infection requiring...
journal_title:Clinical oral investigations
pub_type: 杂志文章
doi:10.1007/s00784-012-0757-6
更新日期:2013-04-01 00:00:00
abstract:OBJECTIVES:The aim of the present study was to investigate different fluorescence-based, two-color viability assays for visualization and quantification of initial bacterial adherence and to establish reliable alternatives to the ethidium bromide staining procedure. MATERIALS AND METHODS:Bacterial colonization was att...
journal_title:Clinical oral investigations
pub_type: 杂志文章
doi:10.1007/s00784-012-0792-3
更新日期:2013-04-01 00:00:00
abstract:OBJECTIVE:Edible oils are an empiric approach for the prevention of oral diseases. The present in situ study investigated the effect of edible oils on initial bacterial colonization of enamel surfaces. METHODS AND MATERIALS:Initial biofilm formation was performed on enamel specimens mounted on maxillary splints and ca...
journal_title:Clinical oral investigations
pub_type: 杂志文章,随机对照试验
doi:10.1007/s00784-012-0734-0
更新日期:2013-03-01 00:00:00
abstract:BACKGROUND:Interleukin 8 (IL-8) is a pro-angiogenic, pro-inflammatory mediator that belongs to the family of chemokines. Due to its pro-angiogenic characteristic, it may play a vital role in tumour angiogenesis and progression. OBJECTIVES:This study was designed to estimate the levels of salivary IL-8 in oral precance...
journal_title:Clinical oral investigations
pub_type: 杂志文章
doi:10.1007/s00784-012-0723-3
更新日期:2013-03-01 00:00:00
abstract:OBJECTIVES:The purpose of this study was to analyze the prevalence of dental erosion among competitive swimmers of the local swimming club in Szczecin, Poland, who train in closely monitored gas-chlorinated swimming pool water. MATERIALS AND METHODS:The population for this survey consisted of a group of junior competi...
journal_title:Clinical oral investigations
pub_type: 杂志文章
doi:10.1007/s00784-012-0720-6
更新日期:2013-03-01 00:00:00
abstract:OBJECTIVES:A multicentric randomized, 3-year prospective study was conducted to determine for how long Biodentine, a new biocompatible dentine substitute, can remain as a posterior restoration. MATERIALS AND METHODS:First, Biodentine was compared to the composite Z100®, to evaluate whether and for how long it could be...
journal_title:Clinical oral investigations
pub_type: 杂志文章,多中心研究,随机对照试验
doi:10.1007/s00784-012-0701-9
更新日期:2013-01-01 00:00:00
abstract:OBJECTIVES:The aim of this study was to evaluate the effect of different seating forces during cementation in cement-ceramic microtensile bond strength (μTBS). MATERIALS AND METHODS:Forty-five blocks (5 × 5 × 4 mm(3)) of a glass-infiltrated alumina-based ceramic (In-Ceram Alumina) were fabricated according to the manu...
journal_title:Clinical oral investigations
pub_type: 杂志文章,随机对照试验
doi:10.1007/s00784-011-0668-y
更新日期:2013-01-01 00:00:00
abstract:OBJECTIVES:Albumin has a known capability to modulate free serum concentrations of proteins produced by tumour cells. The technique of spin probe labelling of albumin followed by electron paramagnetic resonance (EPR) spectroscopy may allow identification of these structural and functional changes, which regularly occur...
journal_title:Clinical oral investigations
pub_type: 杂志文章
doi:10.1007/s00784-011-0655-3
更新日期:2012-12-01 00:00:00
abstract::Smoking is a causative factor in oral squamous cell carcinomas (SCC). Unfortunately, only poor data exist regarding the quality of life of smokers vs non-smokers with SCC. The purpose of this study is to show a correlation between variables for comprehensive interdisciplinary rehabilitation and better patient quality ...
journal_title:Clinical oral investigations
pub_type: 杂志文章,多中心研究
doi:10.1007/s00784-011-0631-y
更新日期:2012-10-01 00:00:00
abstract:OBJECTIVES:Adhesively luted all-ceramic restorations represent a promising way to preserve and stabilize weakened tooth substance, but little information is published about the clinical performance of extensive all-ceramic restorations. MATERIALS AND METHODS:A total of 78 large CEREC 2™ single-tooth all-ceramic restor...
journal_title:Clinical oral investigations
pub_type: 杂志文章
doi:10.1007/s00784-011-0642-8
更新日期:2012-10-01 00:00:00
abstract::The hypotheses tested were: survival rate of fully and partially retained glass-carbomer sealants is higher than those of high-viscosity glass-ionomer, with and without energy supplied, and that of resin composite; survival rate of fully and partially retained sealants of high-viscosity glass-ionomer with energy suppl...
journal_title:Clinical oral investigations
pub_type: 杂志文章,多中心研究,随机对照试验
doi:10.1007/s00784-011-0633-9
更新日期:2012-10-01 00:00:00
abstract::The aim of this study was to evaluate the clinical performance of S(3) Bond (Kuraray Corp., Japan) and G-Bond (GC Corp., Japan) all-in-one bonding agents, over 3 years in non-carious cervical lesions (NCCLs). Ethics Committee approval was obtained, and 60 restorations were placed in 11 patients aged 45-84 years (mean ...
journal_title:Clinical oral investigations
pub_type: 杂志文章
doi:10.1007/s00784-011-0595-y
更新日期:2012-08-01 00:00:00
abstract::The present study focuses on the correlation between the expression pattern of β-catenin (component of Wnt signaling), ΔNp63 (proliferation marker), and Notch 1 (transmembrane receptor) in oral squamous cell carcinoma. The study also aims to investigate the interaction between β-catenin and ΔNp63 in oral cancer. Furth...
journal_title:Clinical oral investigations
pub_type: 杂志文章
doi:10.1007/s00784-011-0605-0
更新日期:2012-08-01 00:00:00
abstract::To present the safety profile, the early healing phase and the clinical outcomes at 24 weeks following treatment of human intrabony defects with open flap debridement (OFD) alone or with OFD and rhGDF-5 adsorbed onto a particulate β-tricalcium phosphate (β-TCP) carrier. Twenty chronic periodontitis patients, each with...
journal_title:Clinical oral investigations
pub_type: 杂志文章,随机对照试验
doi:10.1007/s00784-011-0610-3
更新日期:2012-08-01 00:00:00
abstract::The aim of this study was to evaluate the clinical long-term performance of a visible light-cured resin (VLCR) denture base material and to compare it to a well-established polymethylmethacrylate (PMMA)-based denture acrylic in a randomized split-mouth clinical long-term study. One hundred removable partial dentures i...
journal_title:Clinical oral investigations
pub_type: 杂志文章,随机对照试验
doi:10.1007/s00784-011-0572-5
更新日期:2012-06-01 00:00:00
abstract::The main objective of this study was to identify the risk factors for the incidence of visible caries experience in a cohort of preschool children living in Flanders. Data were collected from 1,057 children; validated questionnaires on oral health-related behaviour were completed by parents at birth (2003-2004), at ag...
journal_title:Clinical oral investigations
pub_type: 杂志文章
doi:10.1007/s00784-011-0579-y
更新日期:2012-06-01 00:00:00
abstract::Acidogenicity and the levels of mutans streptococci (MS) in dental plaque after the use of Lactobacillus rhamnosus GG (LGG) and Lactobacillus reuteri were determined. The study had a randomised, double-blind, crossover design. Thirteen volunteers used tablets containing LGG or a combination of L. reuteri SD2112 and PT...
journal_title:Clinical oral investigations
pub_type: 杂志文章,随机对照试验
doi:10.1007/s00784-011-0584-1
更新日期:2012-06-01 00:00:00
abstract::We determined the effects of soluble or coated nanocrystalline hydroxyapatite paste (nano-HA) and enamel matrix derivative (EMD) on proliferation, adhesion, and migration of periodontal ligament fibroblasts (PDLs). Cultured PDLs were stimulated with nano-HA paste or EMD in a soluble form or were coated to the surface ...
journal_title:Clinical oral investigations
pub_type: 杂志文章
doi:10.1007/s00784-011-0570-7
更新日期:2012-06-01 00:00:00
abstract::The use of the vascularized fibula graft has already been established for reconstruction of the mandible following ablative surgery. In order to reconstruct the vertical height of the alveolar process and improve implant position as well as angulation, some therapeutic options are available, including primary use of t...
journal_title:Clinical oral investigations
pub_type: 杂志文章
doi:10.1007/s00784-011-0582-3
更新日期:2012-04-01 00:00:00
abstract::Periodontal ligament (PDL) cells have been associated with the regulation of periodontal repair processes by the differential expression of osteoprotegerin and RANKL in response to intermittent parathyroid hormone (PTH) resulting in a modified activity of bone-resorbing osteoclasts. Here, we examined the intracellular...
journal_title:Clinical oral investigations
pub_type: 杂志文章
doi:10.1007/s00784-011-0541-z
更新日期:2012-04-01 00:00:00
abstract::This study aims to evaluate the inclinations of right and left sides the mandibular fossa in Asian population using computed tomography (CT) images and determine its effects according to the parameters of gender, age, and asymmetry. CT images of the heads of 198 Asian subjects [95 females aged 44.2 ± 20.7 years, range...
journal_title:Clinical oral investigations
pub_type: 杂志文章
doi:10.1007/s00784-011-0518-y
更新日期:2012-04-01 00:00:00
abstract::This retrospective study investigated the frequency and time history of chipping or facings failure of three-unit and four-unit tooth-supported metal ceramic (MC) fixed partial prostheses (FPDs). Six hundred fifty-four MC FPDs were inserted according to a standardized treatment protocol at the Department of Prosthodon...
journal_title:Clinical oral investigations
pub_type: 杂志文章
doi:10.1007/s00784-011-0511-5
更新日期:2012-04-01 00:00:00
abstract::The objective was to evaluate the development of oral health-related quality of life (OHRQoL) in patients with complete dentures and the association between OHRQoL and patient satisfaction. Fifty-two patients (mean age, 66.3, 48.1% male) received dentures in at least one jaw. The analysis was conducted on participants...
journal_title:Clinical oral investigations
pub_type: 杂志文章
doi:10.1007/s00784-010-0483-x
更新日期:2012-02-01 00:00:00
abstract::The objective of this prospective clinical follow-up was to evaluate the 2-year clinical performance of a nanofilled resin composite in class II restorations. The restorations were made with and without intermediary layer of a nanofilled flowable resin composite studied in an intraindividual comparison. Each participa...
journal_title:Clinical oral investigations
pub_type: 杂志文章,随机对照试验
doi:10.1007/s00784-010-0485-8
更新日期:2012-02-01 00:00:00